Traditional manual calibration mode for mine -used gas sensors is easy to harm persons and has high labor intensity and low operation efficiency, whose calibration precision is greatly influenced by human factors. While existing automatic calibrators based on single chip microcomputer can only calibrate one sensor at the same time, which is applicable for calibrating the same type of sensors in small numbers. For the above problems, an automatic calibration system for mine -used gas sensors is designed. The system is mainly composed of server, upper computer, intelligent calibration cabinet, exhaust control box and exhaust pipe, which realizes automatic batch calibration of mine -used gas sensors with different types at the same time according to presupposed conditions, safe emissions of tail gas and automatic collection and storage of process data. The test results show that: For 0,0.5%,1.5%,3.5%CH4, measurement errors of mine -used low concentration CH4 sensors calibrated by the system are within permissible error range; One intelligent calibration cabinet in the system can synchronously calibrate ten mine -used gas sensors with the same type and links sixty sensors at most. The system realizes unattended calibration process and safe, efficient and fast calibration of mine -used gas sensors.